Synthesis of 3-amino-4,5-dihydro(5H)4-oxothieno[3,2-c]quinoline-2-carboxylic acids and their alkyl esters

Department of Chemistry, M.N.R. P.G. College, Opposite J.N.T.U., Kukatpally, Hyderabad-500 072, India E-mail: jayashree_avc@yahoo.co.in Manuscript received 25 May 2008, revised 12 August 2009, accepted 26 August 2009 4-Hydroxyquloolin-2(H)ones are converted to 4-cbloro-3-eyanoquinolin-2(H)ones and are cyclised with thioglycolie add and Its alkyl esters to furnish the title compounds viz. 3-amino-4,5-dihydro(SH)4-oxothleno[3,2-c]qulnollne-2-carboxylic acids and their corresponding alkyl esters, which are characterised by elemental analysis and spectral data