Signet Ring Cell Adenoma Thyroid – A Case Report

Signet ring cell adenoma is a rare thyroid neoplasm which usually present as a solitary nodule. Histopathologically it can very well be mistaken for a metastatic signet ring cell lesion, as both of them shows cells with intracytoplasmic vacuole and eccentrically pushed nucleus. The intracytoplasmic vacuole in signet ring cell adenoma stain positive for thyroglobulin which help in confirming the diagnosis. Here we describe a case of signet ring cell adenoma of thyroid in a 46-year-old female with its cytological, histological and immunohistochemical features