CYTOGENETIC FEATURES OF CARCINOGENESIS

At present, primary plurality of tumors refers to the presence of several independent malignant or benign neoplasms occurring synchronously or metachronously in one person. Primary multiple malignancies (MPML) can develop in a single organ, in paired organs or organs of the same system, as well as in organs and systems that are not functionally related to each other. Most frequently PMZN are observed in one organ and in the organs of different systems unlike the lesions of paired organs and organs of one system PMZN are extremely complex n poorly studied problem of oncology Their number is increasing with the growth of overall cancer morbidity, increasing life expectancy after curing patients with malignant tumors Probability of primary multiple malignancies in patients who have already had a cancer disease, 6 times higher than in people who the aim of: the present study was to investigate cytogenetic features of carcinogenesis in primary multiple malignancies