Tian, Hao, Li, Xin Ping, Zhao, Jianping, Gao, Hong Wei, Xu, Qiong Ming, Wang, Jian Wen (2021): Biotransformation of artemisinic acid to bioactive derivatives by endophytic Penicillium oxalicum B4 from Artemisia annua L. Phytochemistry (112682) 185: 1-10, DOI: 10.1016/j.phytochem.2021.112682, URL: http://dx.doi.org/10.1016/j.phytochem.2021.11268
Artemisinin, a sesquiterpene lactone, is the active antimalarial constituent of Artemisia annua. Sev...
Biotransformation of artemisinin (1) by Aspergillus niger was investigated. During 12 days at 28 °C ...
Artemisinin, a sesquiterpene lactone produced by Artemisia annua glandular secretory trichomes, is t...
Fig. 8. Proposed biotransformation process of artemisinic acid (AA) by Penicillium oxalicum B4.Publi...
Fig. 1. Structures of artemisinic acid (AA) and its biotransformation metabolites 1–8.Published as p...
Fig. 5. Time course for the biotransformation of artemisinic acid (AA) by Penicillium oxalicum B4. A...
Fig. 6. Cytotoxic activity induced by artemisinic acid (AA) and its derivatives in HL60 (A), LS174T ...
Fig. 4. Time course of mycelial biomass (A) and the biotransformation of artemisinic acid (AA) by Pe...
Fig. 3. Key NOSEY correlations for metabolites 1–4.Published as part of Tian, Hao, Li, Xin Ping, Zha...
Fig. 7. Inhibitory effects of metabolite 4 (A) and 7 (B) on cell viability and LPSinduced nitrite pr...
Fig. 2. Key HMBC and 1H-1H COSY correlations for metabolites 1–5.Published as part of Tian, Hao, Li,...
Artemisinin, a sesquiterpene lactone, is the active antimalarial constituent of Artemisia annua. Sev...
首次研究了大黄毛状根培养体系对青蒿素的生物转化反应.经过培养形成一个转化产物,应用光谱方法鉴定转化产物的结构为去氧青蒿素.The biotransformation of artemisinin by...
Metabolic engineering is an integrated bioengineering approach, which has made considerable progress...
Metabolic engineering is an integrated bioengineering approach, which has made considerable progress...
Artemisinin, a sesquiterpene lactone, is the active antimalarial constituent of Artemisia annua. Sev...
Biotransformation of artemisinin (1) by Aspergillus niger was investigated. During 12 days at 28 °C ...
Artemisinin, a sesquiterpene lactone produced by Artemisia annua glandular secretory trichomes, is t...
Fig. 8. Proposed biotransformation process of artemisinic acid (AA) by Penicillium oxalicum B4.Publi...
Fig. 1. Structures of artemisinic acid (AA) and its biotransformation metabolites 1–8.Published as p...
Fig. 5. Time course for the biotransformation of artemisinic acid (AA) by Penicillium oxalicum B4. A...
Fig. 6. Cytotoxic activity induced by artemisinic acid (AA) and its derivatives in HL60 (A), LS174T ...
Fig. 4. Time course of mycelial biomass (A) and the biotransformation of artemisinic acid (AA) by Pe...
Fig. 3. Key NOSEY correlations for metabolites 1–4.Published as part of Tian, Hao, Li, Xin Ping, Zha...
Fig. 7. Inhibitory effects of metabolite 4 (A) and 7 (B) on cell viability and LPSinduced nitrite pr...
Fig. 2. Key HMBC and 1H-1H COSY correlations for metabolites 1–5.Published as part of Tian, Hao, Li,...
Artemisinin, a sesquiterpene lactone, is the active antimalarial constituent of Artemisia annua. Sev...
首次研究了大黄毛状根培养体系对青蒿素的生物转化反应.经过培养形成一个转化产物,应用光谱方法鉴定转化产物的结构为去氧青蒿素.The biotransformation of artemisinin by...
Metabolic engineering is an integrated bioengineering approach, which has made considerable progress...
Metabolic engineering is an integrated bioengineering approach, which has made considerable progress...
Artemisinin, a sesquiterpene lactone, is the active antimalarial constituent of Artemisia annua. Sev...
Biotransformation of artemisinin (1) by Aspergillus niger was investigated. During 12 days at 28 °C ...
Artemisinin, a sesquiterpene lactone produced by Artemisia annua glandular secretory trichomes, is t...