ISOLATION OF CARDIOTOXIN FROM COBRA VENOM (NAJA TRIPUDIANS; MONOCELLATE VARIETY)

Isolation of an active principle "Cardiotoxin" from cobra venom (Naja tripudians) has been made by fractional precipitation method using different electrolytes such as Na2SO4, NaCI as precipitants and it has been found to be, weight by weight, 15 times more toxic, when compared biologically, than crude cobra venom. The isoelectric point and nature of its charge et different pH values have been determined by the micro-cataphoretic and transport methods, and they agree fairly well