Intraoperative Blood Loss and Blood Transfusion Requirement Among Liver Transplant Recipients. A National Single Center Experience 2020

Background : Liver Transplantation (LT) is a complicated surgical procedure with high risk for massive intraoperative blood loss due to pre-existing coagulopathy, portosystemic shunts with collateral circulations and splenomegaly. The study purpose was to evaluate single center transfusion strategies and to identify the risk factors associated with the intraoperative blood loss and blood transfusion. Methods : Study includes 18 patients who underwent LT at Hospital Selayang between January 2020 and December 2020. Retrospective analysis of data included preoperative assessment of coagulopathy, intraoperative blood loss, blood component transfusion. Results : Mean age in the study group was 36.4 ± 12.68 years. Mean intraoperative blood loss was 4450 ± 1646 ml requiring 4.17 ± 3.3 Packed Red Blood Cell (PRBC) Units, 7.56 ± 5.5 platelet units, and 9.50 ± 6.0 fresh frozen plasma (FFP) units. Independent risk factor for High Blood Loss (HBL) group was lower pre-operative platelet count and it is statistically significant (p = 0.024). HBL group is associated with higher usage of PRBC (p = 0.024) and Platelet Units (p = 0.031) and it is statistically significant. Length of stay (LOS) in ICU averaging 8.6 ± 4.95 days and there is no significant differences comparing the HBL and LBL group (p = 0.552). Mortality < 90 days for all recipients was 22.2%. Conclusion : The pre-operative platelet count for is the most important factor associated with HBL in LT procedure. Usage of PRBC and Platelet units were statistically higher in HBL. Comparing HBL and LBL patients, there is no difference in terms of the LOS in ICU post-operatively. Disclaimer: Abstract text might vary slightly from what is displayed in the e-poster.This poster was submitted to the 14th National Conference for Clinical Research (NCCR) in August 18-20, 2021. https://nccrconference.com.my