Cluster decorated recognition elements on DNA origami for surface enhanced Raman spectroscopic detection methods

The project “DeDNAed” intends to develop a novel, innovative biosensing platform whose advantages and benefits are in terms of sensitivity, versatility and being ultrafast by an optical approach. Our platform will be based on the assembly and integration of sensing elements (transducer and bioreceptor) by DNA origami. The DNA origami will serve as a “nano-breadboard” in order to precisely control the position of these elements and thus the sensor architecture at the nanometer scale. This poster, presented at the University of Potsdam Science Day 11 October 2022, presents the structure of the project and the innovative bioanalytical platform specifically