Study of mixed ligand complexes and kinetic parameters of [Zn-antibiotics-aspirin] system : a polarographic approach

Electrochemical Laboratory, Department of Chemistry, Dr. H. S. Gaur University, Sagar-470 003, India E-mail : amul33in @yahoo.co.in Fax : 91-07582-22163 Manuscript received 10 January 2002. revised 7 August 2{)()2, accepted 27 August 2002 Stability constants and kinetic parameters of ternary complexes of ZnII with neomycin, chlortetracycline, oxytetracycline, tetracycline, penicillin-V and penicillin-G as primary ligands and aspirin as secondary ligand were determined at pH 7.30 ± 0.01 and ionic strength of 1.0 mol dm-3 (NaCIO4) at 25º using polarographic technique. Zn forms 1 : 1 : 1 [Zn-antibiotic-aspirin], 1 : 1 : 2 [Zn· antibiotic-(aspirin)2] and 1 : 2 : 1 [Zn-(antibiotic)2-aspirin] ternary complexes with these ligands. The nature of waves of Zn and its complexes were quasireversiblc