A ligand free protocol using Cu(OAc)2@Mont K-10 as versatile reusable catalyst for efficient homocoupling of arylboronic acids for synthesis of symmetric biaryls

Department of Chemistry, Dibrugarh University, Dibrugarh-786 004, Assam, India E-mail: dr.pradip54@gmail.com, geetikachem@yahoo.co.in Manuscript received 01 July 2018, accepted 16 July 2018 Biaryls are an important class of organic compounds that occur in many natural products and they have a wide variety of applications in drugs, agrochemicals, dyes, semi-conductors, and asymmetric syntheses. A versatile, eco-friendly, recyclable, heterogeneous catalyst has been developed for the efficient synthesis of symmetric biaryls from aryl boronic acids. The de­veloped protocol for homocoupling of aryl boronic acid to symmetric biaryls is based on copper acetate supported on acid activated Mont K-10 which is ligand free, mild, inexpensive and compatible with wide range of functional groups and exhibit excellent yields. The catalyst is characterised by FTIR, ESR, XRD, SEM-EDX, BET surface area measurement and the cata­lyst can be separated from the reaction mixture by simple centrifugation and reused upto five cycles without significant loss in activit