Fig. 3 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea

Fig. 3. Inhibitory effects of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion in T84 cells. (A) Dose response studies of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion. The representative traces of apical ISC on T84 cells are shown. (B) Data were fitted to the Hill equation and expressed as means of % forskolin-stimulated ISC ± S.E.M. (n = 3).Published as part of Dawurung, Christiana J., Noitem, Rattikarn, Rattanajak, Roonglawan, Bunyong, Ratchanu, Richardson, Christopher, Willis, Anthony C., Kamchonwongpaisan, Sumalee, Yimnual, Chantapol, Muanprasat, Chatchai & Pyne, Stephen G., 2020, Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea, pp. 1-11 in Phytochemistry (112464) 179 on page 5, DOI: 10.1016/j.phytochem.2020.112464, http://zenodo.org/record/829352