ANALYSIS OF IMPACT OF METABOLIC SYNDROME IN ASTHMA AND COPD PATIENTS IN PAKISTAN

Introduction: Bronchial asthma and COPD (Chronic Obstructive Pulmonary Disease) are obstructive pulmonary diseases that affected millions of people all over the world. These two illnesses have many similarities and many differences which may sometimes confuse therapists in the diagnostics and management of these diseases which affect more and more people every year worldwide. Aims and objectives: The basic aim of the study is to analyze the impact of metabolic syndromes in asthma and COPD patients in local population of Pakistan. Material and methods: This study was conducted at Children Hospital Complex and Institute of Child Health, Multan during 2018 with the permission of ethical committee of hospital. 100 patients, who were presented with COPD in the Hospital, were included in the study. After approval from ethical committee all the parents were informed for the purpose of the study and a written informed consent was taken from the patients. Their Waist Circumference, Glucose Level (mg/dL), Triglyceride level (mg/dL), High Density Lipoprotein level (mg/dL), Systolic & diastolic blood pressure was measured for the diagnosis of metabolic syndrome. Results: From 100 patients, it was observed that the minimum age was 36 years and maximum age was 65 years with mean and standard deviation of the age was 52.44 ± 7.83 years. The minimum glucose level was 80 mg/dL and maximum was 115 mg/dL with mean and standard deviation was 94.05 ± 11.15 mg/dL. The minimum triglyceride level was 100 mg/dL and maximum was 370 mg/dL with mean and standard deviation was 181.70 ± 88.03 mg/dL. Conclusion: The frequency of metabolic syndrome was found in 43.9% patients with chronic obstructive pulmonary disease. All effect modifiers have significant influence