ROLE OF RECOMBINANT HUMAN INTERLEUKIN-11 IN THROMBOCYTOPENIA ASSOCIATED WITH DENGUE FEVER
- Dr Jazirah Rehmat, Dr. Sidra Naseem, Dr. Ammara Wahab
DOIAbstract
Objective: To determine the role of recombinant human interleukin-11 in raising platelet count in patients with dengue fever associated thrombocytopenia. Methods: This randomized double blind placebo controlled trial was conducted at Fatima Memorial hospital, Lahore. Study duration was July 2011 to October 2011. 40 dengue patients with platelet count <30,000/ml were enrolled in study. All cases were randomly stratified into 2 groups. 1 received rhIL-11 while second group received distilled water (placebo). The outcome was compared between both groups after 48 hours. Results: It was observed that there was relatively better rise in platelet count in group which received rhIL-11 as compared to placebo group. In rhIL-11 receiving group the...
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