Insulinoma - review of characteristics, diagnosis and treatment

Sapuła, Klaudia, Remjasz, Klaudia, Siedlecki, Wojciech, Fabiś, Mateusz, Kuchnicka, Julia, Aleksandrowicz, Jakub, Zielińska, Martyna. Insulinoma - review of characteristics, diagnosis and treatment. Journal of Education, Health and Sport. 2022;12(9):446-453. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.09.051 https://apcz.umk.pl/JEHS/article/view/39720 https://zenodo.org/record/7048397 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.08.2022. Revised: 02.09.2022. Accepted: 04.09.2022. Insulinoma - review of characteristics, diagnosis and treatment Klaudia Sapuła: 0000-0003-2436-0150; Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie Klaudia Remjasz: 0000-0002-0879-7515; Absolwent Warszawskiego Uniwersytetu Medycznego Wojciech Siedlecki: 0000-0002-9917-5411; 1 Wojskowy Szpital Kliniczny w Lublinie Mateusz Fabiś: 0000-0002-7150-1852; Wojewódzki Szpital Specjalistyczny im. M. Kopernika w Łodzi Julia Kuchnicka: 0000-0003-0409-5695; Szpital Specjalistyczny w Brzezinach Jakub Aleksandrowicz: 0000-0002-4534-9682; Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie Martyna Zielińska: 0000-0001-8886-8274; Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie ABSTRACT: Introduction and purpose: Insulinoma is one of a group of pancreatic neuroendocrine neoplasms (NENs). This tumor has its origin in the β cells of the pancreatic islets, which are responsible for the production of insulin. Excessive amounts of this hormone in the body manifest hypoglycemic neuroglycopenic and sympathetic-overstimulation symptoms. The purpose of this review is to analyze information on the characteristics, diagnosis and treatment of patients with insulinoma. Material and methods: This review was based on available data collected in the PubMed database and published between 2017 and 2022. The study was conducted by reviewing keywords as follows: "insulinoma," "NEN," "diagnosis," and "treatment." Results: The diagnosis of insulinoma consists of a typical clinical presentation, biochemical test results indicating hyperinsulinemic hypoglycemia, and presence of a tumor. The treatment targets solutions leading to a complete recovery, usually performing open surgery involving enucleation of the tumor. Conclusions: Despite the characteristic clinical picture, insulinoma is still often a diagnostic problem. It is necessary to work towards improving diagnostic methods and conduct further research into the most effective methods of treating insulinoma. Keywords: insulinoma, treatment, diagnosi