TO STUDY THE THERMODYNAMIC PARAMETERS OF 5-p-CHLOROPHENYLTHIOCARBAMIDO-1-NAPHTHOL AT DIFFERENT CONCENTRATIONS AND DIFFERENT TEMPERATURES IN 70% ETHANOL-WATER MEDIA

Conductivity play vital role in drug diffusion. Thermodynamic parameters affected by substituent’s of drug. Thus recently in laboratory, conductometrically have been investigated thermodynamic parameters of 5-pChlorophenylthiocarbamido-1-naphthol [p-CPTCN] or L3 have been studied at different concentrations in 70% ethanol-water mixture at different temperatures. This work highlights investigation of G, K and µ values. The thermodynamic parameters viz. ΔH, ΔS and ∆G for ion pair formation determined from the value of ion association constant at 298K and 303K. This investigation provided valuable information regarding to solute-solvents, solute– solute and solvent-solvent interaction and effect of dilution from conductrometric measurements of 5-pChlorophenyl -thiocarbamido-1-nahthol. Key Words: Thermodynamic parameters, Dissociation constant, 5-p-Chlorophenylthiocarb -amido-1-nahthol