ANALYSIS OF LAPAROSCOPIC CHOLECYSTECTOMY WITHOUT USAGE OF PROPHYLACTIC ANTIBIOTICS AND AFTER USAGE, VIA COMPARISON OF SKIN INFECTION

Objective: We carried out this study to take analysis of laparoscopic cholecystectomy with no usage of prophylactic antibiotics and after usage of prophylactic antibiotics via comparison ofskin infection rate and infections in the skin structure among the patients going through this procedure. Study Design: Randomized case-control study. Duration and Place: This study was conducted for the duration of one year starting from December, 2017 to November, 2018 in surgical unit of Mayo Hospital, Lahore. Material and Method: Selected a total number of 144 patients randomly from the surgical ward of the hospital. Divided them into two equal groups named as group A and group B. Before anaesthesia induction, Group B prescribed with 10ml normal saline whereas, Group A was given prophylactic cefuroxime 1.50g impaired into 10ml solution. After this no medicine was prescribed to any of the group. Compared the occurrence rate of skin infection and SSI (Skin Structure Infection) in each group. Results: Three patients of group A(4.16%) fostered skin infection and skin structure infection. Whereas, two patients of group B (2.78%) resulted with skin infection and skin structure infection. With P-value equal to one, difference among both groups statistically wasn’t significant. Conclusion:Among patients experiencing laparoscopic cholecystectomy, prescription of prophylactic antibiotic-drugs doesn’t decrease the occurrence rate of skin infections and skin structure infections. Keywords: Skin infection, Skin Structure Infections, Laparoscopic cholecystectomy, Prophylactic antibiotic