Investigation of antimicrobial activity of aqueous extracts of Eclipta prostrata

Investigation of antimicrobial activity of aqueous extracts of Eclipta prostrata S. Prabagar1, J.Nanthakumar2, S. Thuraisingam3, J. Prabagar4 1Industrial Technology Institute, Colombo 7, SRI LANKA. 2Department of Botany, University of Jaffna, SRI LANKA. 3 Post Graduate Institute of Agriculture, University of Peradeniya, SRI LANKA. 4Department of Chemistry, University of Jaffna, SRI LANKA. s.prabagar@yahoo.co.uk, jeyaraninandakumar@yahoo.com, tnsuganya@gmail.com, j_prabagar@yahoo.co.uk ABSTRACT Eclipta prostrata is a small herb distributed in tropical regions of the world. It is commonly known as false daisy. The plant is used in Ayurvedic medicine for skin infections and some non-communicable diseases. Aqueous extraction of plant material such as leaf and whole plant were investigated for anti-microbial activity without changing concentration. Results of study revealed that all extracts had inhibitory activity against E.coli with the clear zone of 1.3cm, which is similar to streptomycin control. Antifungal activity of leaf and whole plant extract of Eclipta prostrata against Aspergillus and Rhizopus showed the inhibitory growth ranged from 23.5 % to 33.30% whereas the leaf extract showed high inhibition than whole plant extract. The findings exhibit that leaf and whole plant aqueous extracts have narrow spectrum activity and there is a possibility in treatment of infectious diseases. Key words: Eclipta prostrata, leaf and whole plant extracts, antimicrobial activity URL: https://www.ijblst.org/papers-published/ijblst-2020-volume-11-issue-