Fig. 10. The binding modes of 1 (A), 7 (B), 8 (C), and galanthamine (D) with AChE (PDB ID: 4M0E). The hydrogen bonds are indicated by red dashed lines. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)Published as part of Zhan, Guanqun, Gao, Biao, Zhou, Junfei, Liu, Tingting, Zheng, Guijuan, Jin, Zhong & Yao, Guangmin, 2023, Structurally diverse alkaloids with nine frameworks from Zephyranthes candida and their acetylcholinesterase inhibitory and anti-inflammatory activities, pp. 1-15 in Phytochemistry (113564) 207 on page 11, DOI: 10.1016/j.phytochem.2022.113564, http://zenodo.org/record/829053
The AChE inhibitory activity of alkaloid extracts and compounds has been in the focus of research on...
Fig. 6. Overlapped top-scored poses for ligands 19 (blue) and crystal structure of tacrine (green) i...
Introduction: Nowadays, acetylcholinesterase inhibitors are commonly used to improve the sympt...
Fig. 1. Chemical structures of the isolated alkaloids 1–26.Published as part of Zhan, Guanqun, Gao, ...
Fig. 2. 1H–1H COSY, key HMBC, and key NOESY correlations of zephyranines A D (1–4).Published as part...
Zhan, Guanqun, Gao, Biao, Zhou, Junfei, Liu, Tingting, Zheng, Guijuan, Jin, Zhong, Yao, Guangmin (20...
Fig. 8. Experimental ECD spectra of zephyranines G–I (7–9), 6-O-ethylnerinine (10) and the calculate...
Fig. 9. ORTEP drawing of the X-ray structures of haemanthamine (18) and (+)-tazettine (24).Published...
Fig. 7. The binding modes of 9 (A), 10 (B) and 11 (C) with human AChE (PDB ID: 4M0F). Hydrogen bond ...
Fig. 5. Proposed biosynthetic pathway of zephyranine A (1).Published as part of Zhan, Guanqun, Gao, ...
Fig. 4. Experimental and calculated ECD spectra of zephyranines A (1) and B (2) and their enantiomer...
Fig. 7. Experimental and calculated ECD spectra of zephyranines C F (3–6), isolated as mixtures of r...
Fig. 6. Linear correlation plots between the experimental and calculated 13C NMR data for two isomer...
Fig. 3. Linear correlation plots between the experimental and calculated 13C NMR data for four isome...
Sixteen new alkaloids belonging to the galanthamine (<b>1</b>–<b>6</b>), plicamine (<b>7</b>–<b>14</...
The AChE inhibitory activity of alkaloid extracts and compounds has been in the focus of research on...
Fig. 6. Overlapped top-scored poses for ligands 19 (blue) and crystal structure of tacrine (green) i...
Introduction: Nowadays, acetylcholinesterase inhibitors are commonly used to improve the sympt...
Fig. 1. Chemical structures of the isolated alkaloids 1–26.Published as part of Zhan, Guanqun, Gao, ...
Fig. 2. 1H–1H COSY, key HMBC, and key NOESY correlations of zephyranines A D (1–4).Published as part...
Zhan, Guanqun, Gao, Biao, Zhou, Junfei, Liu, Tingting, Zheng, Guijuan, Jin, Zhong, Yao, Guangmin (20...
Fig. 8. Experimental ECD spectra of zephyranines G–I (7–9), 6-O-ethylnerinine (10) and the calculate...
Fig. 9. ORTEP drawing of the X-ray structures of haemanthamine (18) and (+)-tazettine (24).Published...
Fig. 7. The binding modes of 9 (A), 10 (B) and 11 (C) with human AChE (PDB ID: 4M0F). Hydrogen bond ...
Fig. 5. Proposed biosynthetic pathway of zephyranine A (1).Published as part of Zhan, Guanqun, Gao, ...
Fig. 4. Experimental and calculated ECD spectra of zephyranines A (1) and B (2) and their enantiomer...
Fig. 7. Experimental and calculated ECD spectra of zephyranines C F (3–6), isolated as mixtures of r...
Fig. 6. Linear correlation plots between the experimental and calculated 13C NMR data for two isomer...
Fig. 3. Linear correlation plots between the experimental and calculated 13C NMR data for four isome...
Sixteen new alkaloids belonging to the galanthamine (<b>1</b>–<b>6</b>), plicamine (<b>7</b>–<b>14</...
The AChE inhibitory activity of alkaloid extracts and compounds has been in the focus of research on...
Fig. 6. Overlapped top-scored poses for ligands 19 (blue) and crystal structure of tacrine (green) i...
Introduction: Nowadays, acetylcholinesterase inhibitors are commonly used to improve the sympt...