SIGNIFICANCE OF EXPRESSION OF PD-L1 AND P53 PROTEINS IN HUMAN PAPILLOMAVIRUS-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA

High-risk human papillomavirus (HPV), causes oropharyngeal squamous cell carcinoma (OSCC), where it is detected in approximately 70% of tumors arising from the lymphoid tissues of the tonsils or the base of the tongue. The study included 76 patients with T1-4N0-3M0 (AJCC, 7th edition) OSCC, who received treatment at the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology and its Tashkent city branch in the period 2015-202