Endometriosis-associated ovarian carcinoma site in particular structures of the abdominal cavity and the pelvis

Aim: The aim of the study was to determine the frequency of the malignant endometrioma transformation in the structures of the abdominal cavity organs and the pelvis. Material and methods: Making use of the hospital database, we have analyzed histopathological results of patients with ovarian carcinoma operated on between 2004 and 2012 at the Oncology Center in Bydgoszcz. In the case of 69 patients meeting the Sampson criteria, endometriosis and ovarian carcinoma were confirmed in one tissue sample. Following a thorough analysis of operation reports and histopathological results, we have observed the presence of carcinoma texture and endometriosis in: the adnexa, rectovaginal septum, sigmoid colon and the rectum, abdominal integuments, urinary bladder. Results: Endometriosis related to the texture of the carcinoma was present in the adnexa of 30 patients (44.7%), in the rectovaginal septum – in 25 (37.3%), in abdominal integuments – in 7 (10.4%), in the sigmoid colon or rectum – in 3 (4.5%) and within the urinary bladder – in 2 (3%); in the case of 2 patients, endometriosis was focused in several sites. Summary: Differences between patients with ovarian carcinomas, either associated with endometriosis or not – concerning the degree of clinical advancement, histopathological type and prognosis – induce one to search for new methods and new schemes of known therapies