Data from: Headache study: The management of chronic headache with referral from primary care to direct access to Magnetic Resonance Imaging (MRI) compared to Neurology services: an observational prospective study in London

Objectives. To evaluate the cost, accessibility and patient satisfaction implications of two clinical pathways used in the management of chronic headache. Intervention. Management of chronic headache following referral from Primary Care that differed in the first appointment, either a Neurology appointment or an MRI brain scan. Design and setting. A pragmatic, non-randomised, prospective, single-center study at a Central Hospital in London. Participants. Adult patients with chronic headache referred from Primary to Secondary Care. Primary and secondary outcome measures. Participants' use of health care services and costs were estimated using primary and secondary care databases and questionnaires quarterly up to 12 months post-recruitment. Cost analyses were compared using generalised linear models (GLM). Secondary outcomes assessed: access to care, patient satisfaction, headache burden and self-perceived quality of life using headache-specific (MIDAS, HIT-6) and a generic questionnaire (EQ-5D-5L). Results. Mean (SD) cost up to 6 months post-recruitment per participant was £578 (£420) for the Neurology group (n=128) and £245 (£172) for the MRI group (n=95), leading to an estimated mean cost difference of £333 (95% CI £253 to £413, p<0.001). The mean cost difference at 12 months increased to £518 (95% CI £401 to £637, p<0.001). When adjusted for baseline and follow-up imbalances between groups, this remained statistically significant. The utilisation of brain MRI improved access to care compared to the Neurology group (p