Fig. 4. Ligand interaction map of the predicted binding mode of 3, and 3D molecular modeling interaction of the 3 in the binding site of the tyrosinase (PDB ID: 2Y9X).Published as part of Li, Xin, Gong, Yuan-Xiang, Feng, Li, Wang, Xin-Jia, Wang, Jing-Wen, Zhang, An-Xin, Tan, Ning-Hua & Wang, Zhe, 2023, Neuropyrones A-E, five undescribed α-pyrone derivatives with tyrosinase inhibitory activity from the endophytic fungus Neurospora dictyophora WZ-497, pp. 1-7 in Phytochemistry (113579) 207 on page 5, DOI: 10.1016/j.phytochem.2022.113579, http://zenodo.org/record/829052
Fig. 7. Structural models of PTP1B-3 complex from 0 to 100 ns of MD. The structures used in the simu...
Tyrosinase (Ty) is a copper-containing enzyme widely present in plants, bacteria, and humans, where ...
Tyrosinase, a copper-containing enzyme critical in melanin biosynthesis, is a key drug target for hy...
Fig. 1. Chemical structures of neuropyrones A–E (1–5).Published as part of Li, Xin, Gong, Yuan-Xiang...
Fig. 3. The inhibitory effects of 1–5 on tyrosinase.Published as part of Li, Xin, Gong, Yuan-Xiang, ...
Li, Xin, Gong, Yuan-Xiang, Feng, Li, Wang, Xin-Jia, Wang, Jing-Wen, Zhang, An-Xin, Tan, Ning-Hua, Wa...
Fig. 2. Key 1 H– 1 H COSY and HMBC correlations of neuropyrones A–E (1–5).Published as part of Li, X...
Fig. 1. Chemical structures of pestalopyrones A–D (1–4).Published as part of Feng, Li, Han, Jing, Wa...
Fig. 3. Key ROESY correlations of pestalopyrones A–D (1–4).Published as part of Feng, Li, Han, Jing,...
Fig. 2. Key COSY and HMBC correlations of pestalopyrones A–D (1–4).Published as part of Feng, Li, Ha...
Feng, Li, Han, Jing, Wang, Jia, Zhang, An-Xin, Miao, Yuan-Yuan, Tan, Ning-Hua, Wang, Zhe (2020): Pes...
Copyright © 2015 Daungkamon Nokinsee et al.This is an open access article distributed under the Crea...
Tyrosinase is a copper-containing enzyme found in plants and bacteria, as well as in humans, where i...
Fig. 4. ΔδRS (δ- δ) values of (R)-MPA ester of 2 and (S)-MPA ester of 2.Published as part of Feng, L...
Fig. 8. (A) The binding mode of 10 (yellow) in complex with mushroom tyrosinase. Hydrogen bonds inte...
Fig. 7. Structural models of PTP1B-3 complex from 0 to 100 ns of MD. The structures used in the simu...
Tyrosinase (Ty) is a copper-containing enzyme widely present in plants, bacteria, and humans, where ...
Tyrosinase, a copper-containing enzyme critical in melanin biosynthesis, is a key drug target for hy...
Fig. 1. Chemical structures of neuropyrones A–E (1–5).Published as part of Li, Xin, Gong, Yuan-Xiang...
Fig. 3. The inhibitory effects of 1–5 on tyrosinase.Published as part of Li, Xin, Gong, Yuan-Xiang, ...
Li, Xin, Gong, Yuan-Xiang, Feng, Li, Wang, Xin-Jia, Wang, Jing-Wen, Zhang, An-Xin, Tan, Ning-Hua, Wa...
Fig. 2. Key 1 H– 1 H COSY and HMBC correlations of neuropyrones A–E (1–5).Published as part of Li, X...
Fig. 1. Chemical structures of pestalopyrones A–D (1–4).Published as part of Feng, Li, Han, Jing, Wa...
Fig. 3. Key ROESY correlations of pestalopyrones A–D (1–4).Published as part of Feng, Li, Han, Jing,...
Fig. 2. Key COSY and HMBC correlations of pestalopyrones A–D (1–4).Published as part of Feng, Li, Ha...
Feng, Li, Han, Jing, Wang, Jia, Zhang, An-Xin, Miao, Yuan-Yuan, Tan, Ning-Hua, Wang, Zhe (2020): Pes...
Copyright © 2015 Daungkamon Nokinsee et al.This is an open access article distributed under the Crea...
Tyrosinase is a copper-containing enzyme found in plants and bacteria, as well as in humans, where i...
Fig. 4. ΔδRS (δ- δ) values of (R)-MPA ester of 2 and (S)-MPA ester of 2.Published as part of Feng, L...
Fig. 8. (A) The binding mode of 10 (yellow) in complex with mushroom tyrosinase. Hydrogen bonds inte...
Fig. 7. Structural models of PTP1B-3 complex from 0 to 100 ns of MD. The structures used in the simu...
Tyrosinase (Ty) is a copper-containing enzyme widely present in plants, bacteria, and humans, where ...
Tyrosinase, a copper-containing enzyme critical in melanin biosynthesis, is a key drug target for hy...