Capitalizing on a recently reported iminosugar-based aza-crown (ISAC) accessed by a double Staudinger azaWittig coupling reaction, we have expanded the structural diversity of this new family of sweet cyclam analogs. Replacement of the two secondary amines linking the iminosugar units by two amide bonds obtained a cyclodimerization by with BOP and DIPEA led to a macrocycle that did not demonstrate efficient Zn2+ chelation unlike the parent ISAC. Introduction of two pyrene moieties on the secondary amines of the parent ISAC yielded a new fluoroionophore that selectively binds Hg2+ in methanol
A variety of cyclam and metal-cyclam-based systems have been investigated for potential in the sensi...
Three new azamacrocyclic-cyclophane hybrid receptors L1, L2, and L3 have been synthesized that incor...
Chapter I describes the application of the Kulinkovich reaction to the synthesis of novel bicyclic c...
International audienceA new family of chiral C2 symmetric tetraazamacrocycles, coined ISAC for Imino...
The synthesis and photophysical properties of the first examples of iminosugar clusters based on a B...
The photophysical and complexing properties of a series of aza-crown fluoroionophores based on couma...
A novel hybrid of azacrown ether-oxabridged fluorogenic chemosensor (L1) has been synthesized: the m...
A multicomponent 1,3-dipolar cycloaddition between heterocyclic aldehydes, amino esters and dipolaro...
A new method for the synthesis of cycloisodityrosine atropisomers I (R1 = CO2Me, R2 = NHBoc), a 14-m...
Organofluorine molecules have been widely applied in various research fields because of the unique p...
Macroheterocycles containing aza-14-crown-4 ether subunit were synthesized by one-step domino reacti...
<div><p>Ligands incorporating a tetraazamacrocycle receptor, a ‘click’- derived triazole and a 1,8-n...
With the endeavor to find new efficient synthetic methods to rapidly access diverse molecular struct...
A new synthetic pathway to 1-(2-[β,d-galactopyranosyloxy]ethyl)-7-(1-carboxy-3-[4-aminophenyl]propyl...
The use of orthogonally protected cyclam and 1,9-dithia-5,13-diazacyclohexadecane macrocycles, in co...
A variety of cyclam and metal-cyclam-based systems have been investigated for potential in the sensi...
Three new azamacrocyclic-cyclophane hybrid receptors L1, L2, and L3 have been synthesized that incor...
Chapter I describes the application of the Kulinkovich reaction to the synthesis of novel bicyclic c...
International audienceA new family of chiral C2 symmetric tetraazamacrocycles, coined ISAC for Imino...
The synthesis and photophysical properties of the first examples of iminosugar clusters based on a B...
The photophysical and complexing properties of a series of aza-crown fluoroionophores based on couma...
A novel hybrid of azacrown ether-oxabridged fluorogenic chemosensor (L1) has been synthesized: the m...
A multicomponent 1,3-dipolar cycloaddition between heterocyclic aldehydes, amino esters and dipolaro...
A new method for the synthesis of cycloisodityrosine atropisomers I (R1 = CO2Me, R2 = NHBoc), a 14-m...
Organofluorine molecules have been widely applied in various research fields because of the unique p...
Macroheterocycles containing aza-14-crown-4 ether subunit were synthesized by one-step domino reacti...
<div><p>Ligands incorporating a tetraazamacrocycle receptor, a ‘click’- derived triazole and a 1,8-n...
With the endeavor to find new efficient synthetic methods to rapidly access diverse molecular struct...
A new synthetic pathway to 1-(2-[β,d-galactopyranosyloxy]ethyl)-7-(1-carboxy-3-[4-aminophenyl]propyl...
The use of orthogonally protected cyclam and 1,9-dithia-5,13-diazacyclohexadecane macrocycles, in co...
A variety of cyclam and metal-cyclam-based systems have been investigated for potential in the sensi...
Three new azamacrocyclic-cyclophane hybrid receptors L1, L2, and L3 have been synthesized that incor...
Chapter I describes the application of the Kulinkovich reaction to the synthesis of novel bicyclic c...