Pathophysiology of Dyslipidemia in Modern Medicine and Its Correlation in Unani Literature

Dyslipidemia is defined as a disorder of lipoprotein metabolism, which includes the deficiency or overproduction of lipoproteins or can be a combination of both. The manifestation of the disorder can be seen as an elevation of plasma cholesterol or triglycerides or both or a low HDL level and sometimes a combination of all three together contributing to the development of atherosclerosis. The Pathophysiology includes any defect in the lipid metabolism either in the form of overproduction of a lipoprotein or a decrease in its catabolism i.e. LDL clearance defect, Defect in Lipolysis and Remnant removal defects etc. In Unani literature, no disease with the name of Dyslipidemia could be found, but going through the treatise one could get familiar with a disease Siman-e-mufrat which actually corresponds to dyslipidemia in many ways. Various eminent scholars have given detailed account of the disease and also, they were aware with the concept of Dasoomat-fid-dam (presence of fats in the blood). With the liability of all of them in the disease, the full-length paper will discuss in detail the pathophysiology in Modern Medicine and pathological co-relation with the diseased process of dyslipidemia in Unani Medicine