Amorphous calcium phosphate nanoparticles for development of 3D printing bio-inks for orthopaedic application

3D printing can be used to mimic structure of bone tissue for various needs of orthopaedics in laboratory conditions. For synthetic bone tissue, bio-ink would consist of inorganic and organic components, and cell containing media. Amorphous calcium phosphate (ACP) was selected for this study as a prospective inorganic filler of the bio-inks because it is precursor of the biological apatite found in bone. Aim of the study was to develop synthesis method of novel ACP nanoparticles with biomimetic bone-like chemical composition and characterize physicochemical properties thereof