ROLE OF EOSINOPHILS IN PARASITIC INFECTIONS

Eosinophilia, a pronounced increase of eosinophils in the blood or tissues, occurs in numerous important circumstances, like allergic diseases, parasitic infections, and cancer. Helminthic parasites are usually the common parasitic infections witch cause eosinophilia apart from two enteric protozoans, Isospora belli and Dientamoebafragilis. Infection with helminthes parasites produces immune effector responses and in a reaction to various stimuli, eosinophils are recruited from the circulation into inflammatory foci, where they modulate immune responses via sequences of mechanisms. The defence against organisms that are too large to be phagocytosed, particularly parasitic helminthes seems to be the primary role of eosinophils. In this article, we will discuss some of the biological features of eosinophils and their role in parasitic infections