Mass spectral studies of 6-substituted-2-methylthio-9-tetrahydrofuranylpurine nucleoside analogues

Department of Chemistry, Lucknow University, Lucknow-226 007, India Medicinal Chemistry Division, Central Drug Research Institute, Lucknow-226 001, India Manuscript received 5 August 1998, accepted 18 November 1998 The mass fragmentation studies of eight compounds of the series 6-substituted-2-methylthio-9-tetrahydrofuranylpurine (1-8) have been carried out. Two types of fragmentation pattern is observed depending on the amino function. The details are reported as model of purine deoxy nucleosides