Determination of Dissociation Constants pKa of Hydroxyquinoline Derivatives

Department of Chemistry, Government of Maharashtra, Ismail Yusuf College, Bombay-400 060 Manuscript received 31 October 1985, revised 21 April 1986, accepted 23 August 1986 Dissociation constants (pKa) of hydroxyquinoline derivatives are determined potentiometrically at two different ionic strengths, pyridine — water mixed solvent media and at 20, 30 and 40°. Henderson —Hasselhalch equation adopting Alberts and Serjant's method was used for calculating these constants