- The present comparative cross sectional study was planned to compare cytokine levels in the tear of patients with acute allergic conjunctivitis

The present comparative cross sectional study was planned to compare cytokine levels in the tear of patients with acute allergic conjunctivitis ( AAC), choronic allergic conjunctivitis ( CAC) and healthy population. Subjects were divided into Group 1 (without allergic conjunctivitis), Group 2 ( with AAC), and Group 3 (with CAC). Tears were collected using Schirmer strips and cytokine analysis &IgE analysis was performed using enzyme linked immune sorbent assay and by fully auto analyser. There were a total of 149 subjects. Cytokine ( IL-2,4,5,8) levels & eosinophil count in the group with acute allergic conjunctivitis were approximately two to five -fold higher than in the group with healthy control group where the cytokines, eosinophil &IgE levels were found lowest (p,