Suppression of puberty with GnRH analogues in adolescents with Gender Dysphoria

Poleszak Julita, Szabat Przemysław, Szabat Marta, Wójcik Magdalena, Boreński Grzegorz, Janowska Małgorzata, Karakuła‑Juchnowicz Hanna. Suppression of puberty with GnRH analogues in adolescents with Gender Dysphoria. Journal of Education, Health and Sport. 2019;9(9):378-385. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3408244 http://ojs.ukw.edu.pl/index.php/johs/article/view/7415 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 25.08.2019. Revised: 30.08.2019. Accepted: 14.09.2019. Suppression of puberty with GnRH analogues in adolescents with Gender Dysphoria Julita Poleszak1*, Przemysław Szabat2, Marta Szabat2, Magdalena Wójcik1, Grzegorz Boreński1, Małgorzata Janowska3, Hanna Karakuła-Juchnowicz3 1 Student Reaserch Group at the I Department of Psychiatry, Psychoteraphy and Early Intervertion, Medical University of Lublin 2 Student Science Club at the Department of Applied Psychology, Medical University of Lublin 3 I Department of Psychiatry, Psychoteraphy and Early Intervertion, Medical University of Lublin * E-mail adres: julita.poleszak@wp.pl ORCID ID: Julita Poleszak https://orcid.org/0000-0002-5166-6262 Przemysław Szabat https://orcid.org/0000-0001-5796-1900 Marta Szabat https://orcid.org/0000-0001-6309-2027 Magdalena Wójcik https://orcid.org/0000-0002-0999-6284 Grzegorz Boreński https://orcid.org/0000-0002-5359-7555 Małgorzata Janowska https://orcid.org/0000-0002-3643-2310 Hanna Karakuła-Juchnowicz http://orcid.org/0000-0002-5971-795X Abstract Introduction: Gender Dysphoria (GD) is defined as a mismatch between biological sex characteristics and gender identity. The percentage of teenagers with doubts about their gender identity has dramatically increased over the past decade. The aim of the study: This article presents the positions of supporters and opponents regarding suppression of puberty with GnRH analogues in GD adolescents. Material and method: Standard criteria were used to review the literature data. The search of articles in the PubMed database was carried out using the following keywords: gender dysphoria, transsexualism, suppression of puberty. Description: Due to the extension of the time needed to shape gender identity, suppression of puberty seems to be a beneficial preventive measure for the development of sexual dysphoria. Adolescents avoid suffering associated with the development of unwanted sex. However, there are numerous concerns about the negative effects of puberty inhibition on bone development, neuropsychological development and future fertility. Summary: The safety and effectiveness of therapy that inhibits puberty is not properly grounded in scientific evidence. There is still a lack of research assessing the long-term effects of administering hormones that interfere with adolescent sexual development. Keywords: gender dysphoria, transsexualism, suppression of pubert