GENDER DISPARITY IN-HOSPITAL COMPLICATIONS AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) OF CULPRIT VESSEL FOR ACUTE CORONARY SYNDROME (ACS)

Introduction: It has been observed that women are at more risk of Post PCI in-hospital complications i.e vascular complications, Death, Post PCI MI, Post PCI Emergency CABG/ re do PCI. This poor outcome in female as compare to male is related to number of factors including older age and higher prevalence of risk factors. Objective: To determine the frequency of male and female undergoing PCI of Culprit Vessel and gender-based comparison of in-hospital post PCI complications in these patients. Study Design: This descriptive case series study was conducted at Coronary Care Units I, II, III Cardiology Ward, Jillani Block and Angiography Ward of Punjab Institute of Cardiology. It was non-probability purposive sampling. A total of 135 PCI of culprit vessels were done from 19 December 2012 to 18 May. All the baseline procedural and biochemical characteristics recorded. Frequency of males and females undergoing PCI of Culprit Vessel during this duration was calculated then these patients were evaluated for Post PCI Complications. Results: Out of total 135 patients undergoing Culprit vessel PCI male 75 (55.55%) were more as compare to female 60(44.44%). Post PCI Complications were significantly higher in females as compare to males. i.e hematoma 35(31.81%) in female as compare to 10(9.09%) in males. MI female 15(13.63%) males 5(4.54%), Death females 2 (3.6%) males 1(1.8%) and CABG 0 (0%) in both males and females. Conclusion: This study shows that in Pakistan PCI of Culprit vessel is more in males as compare to females and females are at increased risk of post PCI complications i.e Vascular complications and Post PCI MI and death but emergency CABG after PCI is the same in both genders. Key Words: Percutaneous Intervention, Culprit Vessel, Gender disparity, Vascular Complications