ANALYSIS OF USE OF NEUROPEPTIDES IN ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN PAKISTAN

Introduction: Many neuropeptides have recently been identified in human and animal airways. These peptides have potent effects on airway caliber, blood vessels, and secretions, raising the possibility that they may be involved in airway diseases such as asthma. Objectives of the study: The basic aim of the study is to analyze the use of neuropeptides in asthma and chronic obstructive pulmonary disease in Pakistan. Methodology of the study: This study was conducted at Children Hospital & Institute of Child Health, Multan during January 2018 to April 2018. This study was conducted with the permission of ethical committee of hospital. In this study we analyze the use of different neuropeptide drugs for asthma and chronic obstructive pulmonary disease. Results: Here we review a few select neuropeptides that have either been shown to impact or have the potential to impact the pathogenesis and progression of either asthma, COPD, or CF. Special emphasis is placed on neuropeptides that have not received much attention, and/or those that have been recently discovered. Conclusion: It is concluded that Neuropeptides continue to be a source of insight and complexity when it comes to airway disease