292.EMERGING ANTIBIOTIC RESISTANCE PATTERN OF E. COLI UTI: A SINGLE CENTER STUDY

Objective: To determine the frequency and patient demographics of multidrug resistant (MDR) urinary tract isolates of Escherichia Coli (E. coli) in a tertiary care hospital. Study Design: Retrospective study Setting: The study was conducted in departments of Medicine and Obstetrics & Gynecology, Madinah Teaching Hospital / University Medical and Dental College, and General Hospital, Faisalabad. Duration of Study: Study was conducted from May 2016 to Sep 2018. Results: In this retrospective study, 187 cases of UTI with a positive culture showing E. coli were identified from 2015 to 2018. Among all the cases of E. coli UTI, frequency of MDR was 66.8% (n=125) and rest 33.2% (n= 62) cases were not MDR UTI. Among the MDR E.coli UTI cases, 99% of the cases were resistant to one or more antimicrobials of the aminoglycoside family (which was statistically significant, p = 0.000). Keywords: UTI, MDR, Muti-drug resistance, E. coli, Gram negative, Urinary infection, Cystitis, Urine cultur