A REVIEW ARTICLE ON NANOPARTICLES AND IT'S APPLICATIONS

ABSTRACT Nanoparticle is novel approach for drug delivery which can achieve better therapeutic action, better bioavailability and reduce toxicity. Nanoparticles are tiny materials whose size ranges from 1-100nm.They can be classified into different classes based on their properties, shapes or sizes. In this review we presented a detailed review about nanoparticles, their types, preparation techniques, evaluation parameters and applications of nanoparticles. Today nanoparticles are successfully used in brain targeting, in cancer therapy etc., nanoparticles gives us an opportunity to enhance patient compliance for better therapy. Several techniques are used for the preparation of Nanoparticles like Solvent Evaporation, Double Emulsification Method, Emulsion – Diffusion method, Nanoprecipitation Method, Coacervation Method, Salting out Method, Dialysis and Supercritical fluid technology. Nanoparticles are subjected to several evaluation parameters such as Zeta potential, Particle size and shape, Drug entrapment efficiency, Yield of nanoparticles, In-vitro, kinetic study, and Stability of Nanoparticles. KEYWORDS: Nanoparticle, Bio availability, Preparation, Evaluation