Clinicohaematological and Biochemical Profile of Anemia in Pediatric Age Group

Background: Anemia is a prevalent hematological disorder in the pediatric population, affecting child health and development. Understanding the clinicohaematological and biochemical profile of anemia in children is crucial for accurate diagnosis and effective management. Methods: This cross-sectional study investigated the clinicohaematological and biochemical profile of anemia in pediatric patients. A sample of 200 children (aged 1-12 years) with confirmed anemia was included. Relevant clinical data, hematological parameters, and biochemical markers were collected. Hemoglobin levels, serum iron, red blood cell indices, and ferritin levels were analyzed. Statistical analysis, including correlation and subgroup comparisons, was performed to identify associations between clinical, hematological, and biochemical variables. Results: The average age of the study's participants was 6.8 years at the time it was conducted. There were 200 individuals in total, including 120 males and 80 women. Hematological testing revealed that iron deficiency anemia accounted for 65% of all cases of anemia. Hemolytic anemia accounted for 20% of all cases of anemia, followed by all other varieties of anemia combined, which accounted for 15%. Using diagnostic criteria that are unique to each type of anemia, we discovered statistically significant differences in hematological parameters. Those with iron deficiency anemia have statistically significantly lower serum iron and ferritin concentrations than those with other forms of anemia (p 0.001). There was evidence of an interaction between hematological and biochemical indicators in cases of juvenile anemia. Conclusion: This study provides insights into the clinicohaematological and biochemical anemia profile in a sample of 200 pediatric patients. Iron deficiency anemia was the most common type, followed by hemolytic anemia and other classes. Hematological and biochemical parameters differed significantly among anemia types, with lower serum iron and ferritin levels observed in iron deficiency anemia cases. The findings emphasize the importance of comprehensive evaluation, including hematological and biochemical parameters, for accurate diagnosis and management of anemia in children. Further research is needed to explore additional contributing factors and develop targeted interventions for prevention and treatment.http://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue7,Article9.pd