A QUASI-EXPERIMENTAL RESEARCH STUDY FOR THE COMPARISON OF PARATHYROID GLAND PRESERVATION IN SITU AND PARATHYROID GLAND AUTO TRANSPLANTATION IN THE PATIENTS OF TOTAL THYROIDECTOMY (MAYO HOSPITAL, LAHORE)

Objective: The aim of the research was the comparison of the auto transplantation of parathyroid gland with the preservation of the parathyroid gland in situ keeping in view the parathyroid gland function preservation in total thyroidectomy patients. Methods: Research design was quasi-experimental which was carried out in the time span of July, 2015 to June, 2017 at Mayo Hospital, Lahore with a sample of 388 patients experienced total thyroidectomy for numerous disorders of thyroid gland. The sample of the research was divided in to two groups A and B respectively having 97 cases of parathyroid glands who were preserved in situ and 291 patients underwent at least one auto transplant of parathyroid gland in ipsilateral sternocleidomastoid muscle. Six months follow-up was carried out for the parathyroid function assessment. We used Fisher's exact test for the comparison of both the groups. Results: Mean age of group A and B was respectively (42.46 ± 15.30) years and (39.16 ± 18.91) years. An overall proportion of male to female was (1:3.5). In the population of Group “A”, permanent hypocalcemia was developed in 3 cases (3.09%); whereas, “B” group had only 1 permanent hypocalcemia case (0.34%). Conclusion: At least one parathyroid gland auto transplantation after total thyroidectomy is a process that has always predictable outcomes linked with the lowest risk of the permanent hypoparathyroidism. Keywords: Total thyroidectomy and Parathyroid auto transplantation