EFFICACY OF LOCALISED APPLICATION OF TRANEXEMIC ACID AND MEFENAMIC ACID TABLET POWDER IN EXTRACTION SOCKETS FOR CONTROL OF POST EXTRACTION BLEEDING AND PAIN:A SPLIT-MOUTH RANDOMIZED CONTROLLED CLINICAL TRIAL

Background: Post extraction bleeding and pain are two common complications in routine dental practice .There are no studies in which Tranexamic acid and Mefenamic acid combination powder is used locally to control post extraction bleeding and pain. Methodology: This study was conducted in 18 patients indicated for orthodontic extraction of mandibular first premolar and right side was the study side in which pre crushed TRANSET MF powder was placed and compared to the left side which was the control side .Post extraction bleeding immediately and 30 min post extraction was compared along with pain using VAS pain scale on 1,2,3,7 th day post extraction.. Results: There was statistically significant difference in time of post extraction bleeding between study side (less time) and the control side .There is statistically significant difference in pain scale less pain perceived in the study side than the control side. Conclusion: This study is the first one to evaluate the efficacy of crushed TRANSET MF Tablet Powder in post extraction sockets and has shown significant results in reducing post extraction pain and bleeding with no local and systemic side effects .Hence this will be a simple and cost effective technique that can reduce both post extraction bleeding and pain