Data from: Deactivation in the posterior mid-cingulate cortex reflects perceptual transitions during binocular rivalry: evidence from simultaneous EEG-fMRI

Binocular rivalry is a phenomenon in which perception spontaneously shifts between two different images that are dichoptically presented to the viewer. By elucidating the cortical networks responsible for these stochastic fluctuations in perception, we can potentially learn much about the neural correlates of visual awareness. We obtained concurrent EEG-fMRI data for a group of 20 healthy human subjects during the continuous presentation of dichoptic visual stimuli. The two eyes' images were tagged with different temporal frequencies so that eye specific steady-state visual evoked potential (SSVEP) signals could be extracted from the EEG data for direct comparison with changes in fMRI BOLD activity associated with binocular rivalry. We additionally included a smooth replay condition that emulated the perceptual transitions experienced during binocular rivalry as a control stimulus. We evaluated a novel SSVEP-informed fMRI analysis in this study in order to delineate the temporal dynamics of rivalry-related BOLD activity from both an electrophysiological and behavioral perspective. In this manner, we assessed BOLD activity during rivalry that was directly correlated with peaks and crosses of the two rivaling, frequency-tagged SSVEP signals, for comparison with BOLD activity associated with subject reported perceptual transitions. Our findings point to a critical role of a right lateralized fronto-parietal network in the processing of bistable stimuli, given that BOLD activity in the right superior/inferior parietal lobules was significantly elevated throughout binocular rivalry and in particular during perceptual transitions, compared with the replay condition. Based on the SSVEP-informed analysis, rivalry was further associated with significantly enhanced BOLD suppression in the posterior mid-cingulate cortex during perceptual transitions, compared with SSVEP crosses. Overall, this work points to a careful interplay between early visual areas, the right posterior parietal cortex and the mid-cingulate cortex in mediating the spontaneous perceptual changes associated with binocular rivalry and has significant implications for future multimodal imaging studies of perception and awareness.EEG Channel LocationsBrainProducts 64 channel EEG electrode locations.bp64_new.locS01 DataSimultaneous EEG-fMRI and MRI data for Subject 01.S01.zipS02 DataSimultaneous EEG-fMRI and MRI data for Subject 02.S02.zipS03 DataSimultaneous EEG-fMRI and MRI data for Subject 03.S03.zipS04 DataSimultaneous EEG-fMRI and MRI data for Subject 04.S04.zipS05 DataSimultaneous EEG-fMRI and MRI data for Subject 05.S05.zipS06 DataSimultaneous EEG-fMRI and MRI data for Subject 06.S06.zipS07 DataSimultaneous EEG-fMRI and MRI data for Subject 07.S07.zipS08 DataSimultaneous EEG-fMRI and MRI data for Subject 08.S08.zipS09 DataSimultaneous EEG-fMRI and MRI data for Subject 09.S09.zipS10 DataSimultaneous EEG-fMRI and MRI data for Subject 10.S10.zipS11 DataSimultaneous EEG-fMRI and MRI data for Subject 11.S11.zipS12 DataSimultaneous EEG-fMRI and MRI data for Subject 12.S12.zipS13 DataSimultaneous EEG-fMRI and MRI data for Subject 13.S13.zipS14 DataSimultaneous EEG-fMRI and MRI data for Subject 14.S14.zipS15 DataSimultaneous EEG-fMRI and MRI data for Subject 15.S15.zipS16 DataSimultaneous EEG-fMRI and MRI data for Subject 16.S16.zipS17 DataSimultaneous EEG-fMRI and MRI data for Subject 17.S17.zipS18 DataSimultaneous EEG-fMRI and MRI data for Subject 18.S18.zipS19 DataSimultaneous EEG-fMRI and MRI data for Subject 19.S19.zipS20 DataSimultaneous EEG-fMRI and MRI data for Subject 20.S20.zipReadmeDataset information.rivalry-eeg-fmri-upload-readme-20170225.pd