A RESEARCH TO ESTABLISH AN ASSOCIATION BETWEEN LIPID PROFILE AND INCIDENCE OF DIABETES AMONG GENERAL POPULATION OF PAKISTAN

Background and Objectives: Pakistan faces the major issue of emerging Diabetes Mellitus (DM) among the general population with an affected population of seven million which will cross the figure fourteen million by 2040. This increase in the diabetic patients’ places Pakistan among eight highly affected countries. These countries are under a diabetic burden with an increasing number of patients affected by diabetes. In this particular research, we aim to assess the levels of TG and lipid profile among diabetic patients and their interdependence. Methodology: We completed this research in the timeframe of March 2017 to November 2017 at Fatima Jinnah Medical University Lahore on a total of one hundred patients who visited the OPD of the hospital. We documented the information about the one hundred patients of diabetes in the nine months during this research. The research sample consisted of both males and females. The patients were enrolled in the age bracket of (35 – 65) years. Clinical investigations included serum TC, fasting glucose plasma, serum TG, serum LDL-C and serum HDL-C calculated through Randox kit. Results: We conclude that there is a significant and strong association of diabetic retinopathy severity with serum TC, fasting glucose plasma, serum TG, serum LDL-C and serum HDL-C; whereas, diabetes mellitus duration and age also showed a positive and moderate relation with diabetes severity. Conclusion: As per the research outcomes we conclude that a significant and strong association of diabetic retinopathy severity with serum TC, fasting glucose plasma, serum TG, serum LDL-C and serum HDL-C. A strong positive association was also persistent among HbA1c and BSF with serum TC, serum TG, serum LDL-C; while, serum HDL-C had a negatively weak relation with HbA1c and BSF. Keywords: Fasting, Diabetes, Lipids, Glucose, Serum and Cholesterol