COMPLICATIONS OF PARAPHYENYLINE DIAMINE POISONING

Objective: To determine the frequency of complications in cases with paraphyenylene diamine poisoning. Methods: This was a cross sectional study carried out from January 2016 to December 2016 at Sheikh Zayed hospital, Rahim Yar khan. This paraphyenylene diamine poisoning was assessed by the history of its intake from the patients or family. The cases of any gender and age with adult range of 18 years or more were included. The cases with end stage renal or liver failure were excluded. These cases were then assessed to look for various complications in the form of acute renal failure, arrhythmias, dysphagia, edema, acute hepatitis and hyperkalemia. Results: In this study there were 100 cases of paraphyenylene poisoning. Out of these 72 (72%) were females and the mean age of the cases was 29.33±6.57 years and mean duration of poisoning before presentation to hospital was 7.11±1.02 hours. The overall complications were seen in 78 (78%) of the cases and majority of the cases had overlapping of more than one complications. The most common complication was dysphagia which was seen in 47 (47%) of the cases followed by cardiac arrhythmia which was seen in 23 (23%) of cases. acute renal failure and hyperkalemia were seen in 12 and 11% of cases and 2 (2%) of cases died due this poisoning. Conclusion: Paraphyenylene poisoning is common in developing counties and almost all the cases developed some complication and most frequent one was dysphagia. Key words: Paraphyenylene diamine, ARF, Dysphagia, Hepatiti