ANALYSIS OF LEVEL OF ANTIOXIDANTS IN CERVICAL CANCER FEMALE PATIENTS AFTER RECEIVING RADIO THERAPY

Introduction: Cancer of the cervix tends to occur during midlife in women, with half of the patients diagnosed between 25 to 65 years of age. CaCx rarely affects women under the age of 20. Cancer is a group of diseases characterized by uncontrolled growth and spread of abnormal cells. Objectives of the study: This study aim to investigate the level of antioxidants in cervical cancer female patients after receiving radio therapy. Materials and methods: The whole experimental work was conducted at Bahawal Victoria hospital, Bahawalpur during Jan 2018 to May 2018 with the permission of ethical committee. Those cervical cancer patients who receiving radiotherapy were selected to study the antioxidants status in the diseased condition. This study group was divided into further two groups for analysis. Results: The data present in this table explains the levels of antioxidants in cervical cancer females. The data suggest that lipid peroxidation is increases in cervical cancer. The reason is due to high damage of membrane and lipid peroxidation poducts. Conclusion: By reducing oxidative stress, antioxidants counteract the effects of chemotherapy-induced oxidative stress on the cell cycle and enhance the cytotoxicity of antineoplastic agents. Increased ratio of Cu/Zn is due to the significant decrease in Zn and concomitant increase in copper