DDIG Singularity container for predicting of disease-causing indels, nonsense, and synonymous variants

This is a container image that runs DDIG version 3.1. DDIG supports prediction of protein-coding non-frameshifting (NFS) indels, frameshifting (FS) indels, nonsense (protein-truncating) and synonymous (same-sense, silent) variants in the GRCh37/hg19 assembly of the human genome. $ singularity run-help ddig.sif --- If you use DDIG for synonymous variants, please cite: M. Livingstone*, L. Folkman*, Y. Yang, P. Zhang, M. Mort, D. N. Cooper, Y. Liu, B. Stantic, and Y. Zhou, "Investigating DNA, RNA and protein-based features as a means to discriminate pathogenic synonymous variants.", Human Mutation 38: 1336-1347 (2017). [https://doi.org/10.1002/humu.23283] --- If you use DDIG for FS indels and nonsense variants, please cite: L. Folkman, Y. Yang, Z. Li, B. Stantic, A. Sattar, M. Mort, D. N. Cooper, Y. Liu, and Y. Zhou, "DDIG-in: detecting disease-causing genetic variations due to frameshifting indels and nonsense mutations employing sequence and structural properties at nucleotide and protein levels.", Bioinformatics, 31 1599–1606 (2015). [https://doi.org/10.1093/bioinformatics/btu862] --- If you use DDIG for NFS indels, please cite: H. Zhao*, Y. Yang*, H. Lin, X. Zhang, M. Mort, D. N. Cooper, Y. Liu and Y. Zhou, "DDIG-in: Discriminating between disease-associated and neutral non-frameshifting micro-indels", Genome Biology 14 , R43 (2013). [https://doi.org/10.1186/gb-2013-14-3-r23] *equal contribution