This study has discovered a new mechanism that involves inhibiting the organelle, the lysosome, and dormant that cell. This opens the way for lysosomes to potentially be used as a therapeutic target. Tens of thousands of people around the world receive bone marrow transplants each year to help treat leukemia. High doses of chemotherapy are used to quickly kill cancer cells, but they also kill the stem cells needed to reproduce healthy blood. Stem cell transplantation is used to regenerate a patient's healing blood source, but finding the right donor can be challenging, especially in different ethnic communities where the donor list may not be extensive or non-existent. Stem cells in cord blood are of considerable value as additional donor s...
The capacity of pluri-potent stem cells to repair the tissues in which stem cells reside holds great...
The bone marrow (BM) niche encompasses multiple cells of mesenchymal and hematopoietic origin and re...
Cancer stem cells (CSCs) are gaining prominence in oncology. The characterization of the molecular p...
Novel cell-based and gene therapies represent promising approaches for the treatment of incurable di...
Stem cell therapy has been used to treat several types of diseases, and it is expected that its ther...
The research team made the discovery by conducting an in-depth mechanical study of lysosomes, which ...
New understanding of the basic nature of malignancy is emerging due to novel studies drawing from st...
Leukemia as one of the common cancers is still studied and needs improvement in diagnosis and treatm...
Since the discovery of leukemic stem cells (LSCs) over a decade ago, many of their critical biologic...
Hematopoiesis is initiated by a rare population of hematopoietic stem cells (HSC) in the bone marrow...
Despite recent advances, treatment of leukemia is often not curative. New insights indicate that thi...
Cancer lethality is mainly due to the onset of distant metastases and refractoriness to chemotherapy...
Mounting evidence from the literature suggests the existence of a subpopulation of cancer stem cells...
A groundbreaking study led by engineering and medical researchers at the California South University...
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been considered ...
The capacity of pluri-potent stem cells to repair the tissues in which stem cells reside holds great...
The bone marrow (BM) niche encompasses multiple cells of mesenchymal and hematopoietic origin and re...
Cancer stem cells (CSCs) are gaining prominence in oncology. The characterization of the molecular p...
Novel cell-based and gene therapies represent promising approaches for the treatment of incurable di...
Stem cell therapy has been used to treat several types of diseases, and it is expected that its ther...
The research team made the discovery by conducting an in-depth mechanical study of lysosomes, which ...
New understanding of the basic nature of malignancy is emerging due to novel studies drawing from st...
Leukemia as one of the common cancers is still studied and needs improvement in diagnosis and treatm...
Since the discovery of leukemic stem cells (LSCs) over a decade ago, many of their critical biologic...
Hematopoiesis is initiated by a rare population of hematopoietic stem cells (HSC) in the bone marrow...
Despite recent advances, treatment of leukemia is often not curative. New insights indicate that thi...
Cancer lethality is mainly due to the onset of distant metastases and refractoriness to chemotherapy...
Mounting evidence from the literature suggests the existence of a subpopulation of cancer stem cells...
A groundbreaking study led by engineering and medical researchers at the California South University...
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been considered ...
The capacity of pluri-potent stem cells to repair the tissues in which stem cells reside holds great...
The bone marrow (BM) niche encompasses multiple cells of mesenchymal and hematopoietic origin and re...
Cancer stem cells (CSCs) are gaining prominence in oncology. The characterization of the molecular p...