A Review on Various Analytical Methodologies for Buspirone

Buspirone is a psychotropic drug which belongs to the class of compounds known as azaspirodecanediones. Buspirone used primarily as an anxiolytic. It specifically used for generalized anxiety disorder. As an anxiolytic drug buspirone is as potent as benzodiazepines, but it does not cause the adverse side effects, for example sedation, anti-convulsion or muscle relaxation. Buspirone was first approved in 1986 by USFDA. Therefore, the main objective of this analysis of Buspirone in pharmaceutical and biological formulation is in both qualitative and quantitative terms. In this review article, we have summarized UV/Vis spectroscopy, high- performance liquid chromatography (HPLC), High-performance thin-layer chromatography (HPTLC), Liquid chromatography-mass spectroscopy-mass spectroscopy (LC-MS/MS) etc. based methods for estimation of Buspirone. In addition to that, we have discussed the bioanalytical methods for Buspirone analysis. In conclusion, this review article will help to research scholars for further method development for drug estimation in pharmaceutical dosage forms and biological fluids