NANO-ANTIANGIOGENESIS IN CANCER THERAPY

ABSTRACT Cancer angiogenesis is the growth of new blood vessels that tumors need to grow. This process is caused by the release of chemicals by the tumor and by host cells near the tumor. Antiangiogenesis can treat the cancer from the root cause and design of the potent anti angiogenic agents in the nano-form will give a target specific action, decreasing the side effects. In this review, an overview of mechanism of antiangiogenic treatment and role of nanoformulations is being presented. Studies on nano-antiangiogenesis will advance our understanding of the molecular level treatment of tumor angiogenesis and may identify novel and effective targets for the clinical applications of different types of cancers. KEYWORDS: Tumor angiogenesis, Cancer, Nanoparticles