STUDY TO KNOW THE ASSOCIATION OF PULMONARY TUBERCULOSIS WITH DIABETIC AND NON DIABETIC PATIENTS

Objective: To evaluate diabetes mellitus effects on clinical diagnostic methods and to know the association of Pulmonary Tuberculosis with diabetic and non-diabetic patients. Study Design: A cross-sectional retrospective. Place and Duration: In the Pulmonology and Endocrinology Department of Mayo Hospital, Lahore for 2 years duration from 2015-2017. Methodology: Clinical trials of patients with pulmonary TB proven diagnosis were reviewed. Clinical, diagnostic methods, Demographic data and findings on radiology were studied. High-resolution pulmonary computerized tomography (HRCT) and Radiologic data were performed by two different radiologists. After data entry on SPSS-16, the chi-square test and Fischer exact test were used for two groups comparison (TB without DM and TB). P value less than 0.05 was taken significant. Findings: 200 total patients with pulmonary TB, 80 (% 40) had TB and synchronous DM (PTDM group). The mean age of the two groups was not different significantly. The incidence of DM and TB in women was higher significantly (P value 0.05). Multi-lobal cavities were significantly more recorded in diabetics (p value = 0.015). There was no statistically difference between the two groups. Conclusion: Tuberculosis in diabetic patients may be more invasive, in women especially, so more measures should be taken on it. Keywords: Tuberculosis, Diabetes mellitus, radiological findings