Relationships between geomagnetic Ар-indeх and parameters of the immunity in patients with neuroendocrine-immune complex dysfunction in former sportsmen

Tserkovniuk R., Yanchij R., Plyska O., Kovbasnyuk M., Chendey I., Popovych I., Hagner-Derengowska M., Zukow X., Kałużny K., Muszkieta R., Zukow W. Relationships between geomagnetic Ар-indeх and parameters of the immunity in patients with neuroendocrine-immune complex dysfunction in former sportsmen. Journal of Education, Health and Sport. 2021;11(7):335-348. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.07.034 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2021.11.07.034 https://zenodo.org/record/5855875 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2021; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 10.07.2021. Revised: 20.07.2021. Accepted: 30.07.2021. Relationships between geomagnetic Ар-indeх and parameters of the immunity in patients with neuroendocrine-immune complex dysfunction in former sportsmen Ruslan Tserkovniuk1, Roman Yanchij2, Oleksandr Plyska3, Marta Kovbasnyuk2, Ivanna Chendey4, Igor Popovych1,2, Magdalena Hagner-Derengowska5, Xawery Zukow6, Krystian Kałużny7, Radosław Muszkieta5, Walery Zukow5* 1Ukrainian Research Institute for Medicine of Transport, Odesa, Ukraine 2OO Bohomolets’ Institute of Physiology, Kyїv, Ukraine 3National Pedagogical Dragomanov University, Kyїv, Ukraine 4Danylo Galyts’kyǐ National Medical University, L’viv, Ukraine 5Nicolaus Copernicus University, Toruń, Poland 6Medical University of Bialystok, Bialystok, Poland 7Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland *w.zukow@wp.pl Abstract Background. The effect of geomagnetism on human immunity has so far been studied through long-term observations. Recently, we have been detected the immediate immunotropic effects of the disturbances of the geomagnetic field (Ap-index) at multiple sclerosis patients. The aim of this study was to identify the immunotropic effects of geomagnetism on another contingent of people. Material and methods. The object of observation were 21 men (24-63 y) and 20 women (33-62 y) with neuroendocrine-immune complex dysfunction. Each patient was tested twice with an interval of 4 days. Observations were carried out on 09.06. and 13.06. 2015, 14.09 and 18.09. 2015, 27-28.03. and 04-05.04. 2018, 28.01. and 01.02. 2019. Retrospectively we recorded the geomagnetic Ap-Index on the day of testing and during the previous 7 days, using resource https://www.spaceweatherlive.com/. The content of subpopulations of lymphocytes expressing CD3, CD4, CD25, CD8, CD22 and CD56 receptors as well as the serum concentration of circulating immune complexes, immunoglobulins classes M, G, A, C-reactive protein and IL-1β was determined. The state of phagocytic function of neutrophils estimated by microbial count and phagocytic and killing indices against Staphylococcus aureus and Escherichia coli. Results. During the week, the average level of Ap-index ranged from 7 to 13 nT. Maximum coefficients of multiple correlation with immunity parameters were detected for Ap-index on the eve of blood sampling (R=0,768) and 5 days before it (R=0,758) while the minimum on 3 (R=0,541) and 2 (R=0,479) days before sampling. The canonical correlation between Ap-indices for 7 days before and on the day of testing, on the one hand, and the immunity parameters - on the other hand, was very strong: R=0,921; R2=0,849; χ2(200)=375; p