Synthesis of Quinazolone Substituted Amides and Piperazonium Salts of Quinazolone Substituted Acids as Possible Anticonvulsants

Chemistry .Department, Lucknow University Department of Pharmacology and Therapeutics, K. G. Medical College, Lucknow Manuscript received 18 Jane 1977, revised 9 December 1977, accepted 21 March 1978 Some amides and piperazonium salts of quinazolone substituted acids were prepared and screened for anticonvulsant activity against pentylenetetrazol induced seizures. Except two amides, the rest of the compounds showed lower protection than the corresponding acids