COMPARSION OF LIPID PROFILE IN DIABETIC HYPERTENSIVES VS DIABETIC NORMOTENSIVES

Background: Lipid abnormalities are linked to a higher risk of cardiovascular disease and other morbidity in people with diabetes. Dyslipidemia may signal the onset of Type 2 diabetes in the future. A trio of diminished high density lipoprotein (HDL), increased triglycerides (TG), and increased low density lipoprotein (LDL) is known as diabetic dyslipidemia. As a result, diabetic dyslipidemia serves as a separate risk factor and predictor for coronary artery disease (CAD). Aim: To compare Serum lipid profile levels in type-2 diabetics with hypertension (Group 1) and type-2 diabetics without hypertension (Group 2). Methods: Prospective observational study was undertaken on 200 subjects aged 40-60 years from November 2019 to October 2020 with patients of Type-2 diabetes mellitus (both old and new cases) with hypertension (Group 1) and Type-2 diabetes mellitus without hypertension (Group 2) having any of the complications associated with diabetes and on age and sex matched diabetics without hypertension. Results: Mean value of total cholesterol ± standard deviation of Group 1 was 188.92 ± 34.66 mg/dl and that of Group 2 was 190 ± 46.54, the difference between the two groups being statistically not significant (p=0.853). Mean value of triglycerides ± standard deviation of Group 1 was 214.81 ± 78.35 mg/dl and that of Group 2 was 184.04 ± 62.69 mg/dl, the difference between the two groups being statistically highly significant (p=0.003). Mean value of LDL ± standard deviation of Group 1 was 104.42 ± 31.26 mg/dl and that of Group 2 was 109.57 ± 39.78 mg/dl, the difference between the two groups being statistically not significant (p=0.309). Mean value of HDL ± standard deviation of Group 1 was 42.98 ± 6.20 mg/dl and that of Group 2 was 43.80 ± 6.47 mg/dl, the difference between the two groups being statistically not significant (p=0.361). Mean systolic and diastolic blood pressure in Group 1 was 127.64 ± 13.41 and 86.20 ± 7.06 mmHg and that of Group 2 was 118 ± 10.80 and 77.52 ± 7.87 mmHg, the difference between the two groups being statistically highly significant (p