DEMOGRAPHICAL AND CLINICAL PROFILE OF PATIENTS WITH VARIOUS HEMATOLOGICAL DISORDERS

Objective: To evaluate the demographical and clinical profile of patients with various hematological disorders. Patients and Methods: This one year cross sectional study was conducted at tertiary care hospital for the evaluation of various haematological disorders. Complete clinical data were recorded including detail history, clinical examination and haematological study along with specific investigations and proforma filled. All the patients of ≥12 years of age, either gender presented with prolonged fever, repeated infections, unexplained weight loss, refractory anemia, recurrent bleeding episodes and on blood complete picture (CBC) had abnormalities of red blood cells /hemoglobin, white blood cells, platelet count for long duration along with abnormal peripheral smear shown the atypical / blast cells were recruited and enrolled in the study to had bone marrow aspiration & biopsy. The frequency and percentages was calculated while the numerical statistics were used to compute mean ±SD. Results: During one year study period total thirty patients diagnosed with various haematological disorders were observed. The mean age ±SD for whole population was 42.92±7.97, of thirty individuals 18 (60%) were males and 12 (40%) were females. The common clinical presentation identified as Pallor (83.3%), fever with night sweats (66.6%), recurrent infections (63.3%), loss of appetite (76.6%) and weight loss (70%). Regarding hematological disorders, megaloblastic anemia (13.3%), aplastic anemia (26.6%), acute myeloid leukemia (13.3%), myelo-proliferative disorders (13.3%) and lympho-proliferative disorders (16.6%). Conclusion: The common hematological disorders detected were megaloblastic anemia, aplastic anemia, acute myeloid leukemia, myelo-proliferative disorders and lympho-proliferative disorders while the bone marrow biopsy is a safe and simple diagnostic procedure. Keywords: Hematological disorders, Bone marrow biopsy and Bone marrow aspiration