COVID-19 in periodontal patients

Perszke, Michał, Egierska, Dominika. COVID-19 in periodontal patients. Journal of Education, Health and Sport. 2022;12(9):104-112. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.09.014 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.09.014 https://zenodo.org/record/7030586 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 07.08.2022. Revised: 10.08.2022. Accepted: 28.08.2022. COVID-19 in periodontal patients Michał Perszke Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu https://orcid.org/0000-0002-8836-1462 Dominika Egierska Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu https://orcid.org/0000-0002-0465-5982 Abstract Periodontitis is a complex multifactorial disease. COVID-19 pandemic prompted researchers to look for a relationship between SARS-CoV 2 infection and periodontal diseases. The SARS-CoV 2 pathomechanism is associated with the ACE2 receptor, which is highly expressed in periodontal patients. The virus causes a cytokine storm which is also seen in periodontitis. Periopathogen proteases can degrade the S protein of the virus, which facilitates its entry into the host cell. In addition, galectin-3, a protein present in periodontitis, is morphologically similar to the S protein of the virus, which may cause the easier attachment of the virus with the host cell more easily and increase the immune response. In patients infected with SARS-CoV 2, oral lesions such as erosions, ulcers, petechiae, acute parotitis and necrotizing gingivitis occur. The aim of the study is to present the latest reports on the possible mechanisms of the influence of periodontal diseases on the infection and course of SARS-CoV 2 infection and to describe cases of changes in the oral cavity in the course of COVID-19. Keywords: COVID-19, SARS-CoV-2, periodontiti